InOut Biome, LLC Gut microbiome sampling
Ingestible Capsule
Mechanical - Single Use
InOut represents a groundbreaking non-invasive ingestible capsule designed for the sampling of gut microbiomes in localized areas and content. This innovative technology is applicable for both animals and humans.
The InOut delayed-action and enteric-action ingestible capsules are specifically crafted for utilization in an ambulatory research and development setting. Following use, the capsule is retrieved from the stool for analysis, refrigerated until it undergoes analysis, or kept at ambient temperatures for up to 7 days if microbiota stabilization is included.
Fecal samples obtained from stool represent a complex amalgamation of the entire digestive process, hindering progress in understanding the microbiome and its crucial role in life, health, and disease.
InOut, a non-invasive method, captures localized upstream microbiota and content from the chyme rather than relying on fecal samples. This approach allows for convenient repetition using one or more capsules at a time.
InOut Capsules offer a valuable means to assess microbiota communities and bodily fluid content before and after diets, during and after medical treatments. Its simplicity positions it as a significant asset to the burgeoning DNA and microflora testing industry.
InOut emerges as an unparalleled tool in medical diagnostics, treatment, and research. It presents the option of using immediate or delayed action capsules independently or in a series, catering to individuals or groups and allowing for repeatability at home or in a clinic. This method facilitates the collection of otherwise inaccessible microbe stains within their natural environment, enabling the sampling of virus mRNA before degradation in the intestines. The advent of InOut opens the door for the application of metagenomic techniques on localized materials.
The inception of InOut stemmed from my necessity to sample microbiota and bodily fluids in the small intestine, encountering the absence of a practical method to achieve this. Current practices and methods are both invasive and incomplete, lacking a non-invasive means for localized gastrointestinal sampling. Astonishingly, the medical, clinical, and research communities rely solely on samples obtained through mouth swabs, anal swabs, stool, and endoscopic procedures.
Our technology addresses this gap in a stepwise manner, providing a solution at the research level. InOut stands as an innovative approach to non-invasive localized gastrointestinal sampling, revolutionizing the way we gather essential data for medical, clinical, and research purposes.
The global demand for our technology is substantiated by comprehensive market reports, extensive research, medical publications, and the active involvement of the National Science Foundation I-Corp in the market. Our verification process includes conducting over 100 interviews with diverse stakeholders, including global pharmaceutical professionals, medical conference attendees, physicians, gastroenterologists, researchers, testing laboratories, and animal health companies. This widespread engagement underscores the universal recognition and significance of the need for our solution across various sectors.
“All disease begins in the gut.”
―Hippocrates 460 BC ~ 370 BC
A novel, medically disruptive, medical device.
We are actively seeking strategic relationships for the advancement of our technology. Our intellectual property (IP) portfolio is robust, encompassing US and foreign patents, and patent pending.
Should your company express interest, we are ready to provide a comprehensive product overview and are willing to initiate a Non-Disclosure Agreement (NDA) to share full details.
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