InOut is a novel non-invasive ingestible capsule used to sample localized gastrointestinal microbiota and content for medical diagnostics, treatment, research, and precision medicine.
The InOut timed action or delayed enteric action ingestible capsule is designed to be used at home or clinic. The user consumes the capsule, recovers it from the stool, places it in the protective container, and sends or takes it to an attending lab, clinic, doctor, or researcher for analysis.
Endoscopic sampling methods require anesthesia, risk, recovery, and high costs in a clinic or hospital setting. Even then, the most remote areas of the small intestine cannot be reached.
Fecal samples from stool are a complicated amalgamation of the total digestive processes and thwarts advances toward understanding the microbiome and its role in life, health, and disease.
InOut non-invasive methods captures localized upstream microbiota and content from the chyme instead of feces and can be repeated at will with one or more capsules at a time.
InOut Capsules can be used to determine microbiota communities and bodily fluid content before and after diets, during and after medical treatments, and its simplicity makes it a boon to the DNA and microflora testing industry.
InOut is an unparalleled tool for medical diagnostics, treatment, research and individualized medicine. Consider immediate and differing delayed action capsules used alone or in series with one individual or any number of individuals repeatable at home or clinic. Obtain otherwise unavailable samples of microbe stains within their environment; sample virus mRNA before it degrades in the upper intestines. Shotgun metagenomics and high-throughput sequencing techniques can finally be used on localized material.
The idea for InOut was fostered by my need to sample microbes and bodily fluid located in the small intestine and finding there was no practical way to do it. Present practice and methods are invasive and incomplete. No method exists for non-invasive localized gastrointestinal sampling. Incredibly the medical, clinical, and research professions are limited to samples provided by mouth swabs, anal swabs or stool, and endoscopic procedures,
The need is verified by market reports, research and medical publications, and National Science Foundation I-Corp market participation including over 100 interviews with global pharma medical conference attendees, physicians, gastroenterologists, researchers, testing laboratories, and veterinarians.
Assembling the puzzle to achieve commercial production of the InOut capsule nears completion:
We wish to enter into strategic relationships with our technology. We have a path to commercial production, optional turnkey manufacturing with robotic assembly, and FDA registration as a Class 1 or Class 2 medical device with US global companies; including time frames and costs. We have a robust IP position with a US patent and foreign patents pending.
Proof of Concept results charts, and metagenomic sequencing Advanced Analysis Reports are available.
If you are interested, we can provide a product overview and offer to enter into a NDA with you company to provide you with full details. Our objective is to secure an exclusive period of evaluation and dealing, something we are currently prepared to provide.