InOut Biome, LLC Gut microbiome sampling
Ingestible Capsule
Mechanical - Single Use
Advancing Localized Intestinal Sampling
A New Way to Access the Hidden Microbiome
Most microbiome studies rely on fecal samples, even though they reflect only the final stage of digestion. Many microbial communities, metabolites, and biochemical signals active in the small intestine never appear in stool.
InOut Biome™ provides a practical, non-invasive approach to collect localized intestinal samples—capturing the microbial and molecular environment directly at the site of interest.
Why Localized Sampling Matters
The upper intestine and small bowel contain dynamic communities of:
- Microbiota
- Metabolites
- Enzymes
- Viral and fungal elements
- pH-sensitive pathways
Many of these signatures are altered or lost before reaching feces.
Localized sampling offers a more accurate view of:
- Microbial networks and co-occurrences
- Metabolite and enzyme activity
- Regional microbiome variation
- Early biochemical events
- Functional processes not reflected in stool samplesThe InOut Sampling Capsule
The InOut Sampling Capsule
Our ingestible capsule is engineered to:
- Collect site-specific intestinal content
- Stabilize microbiota, metabolites, enzymes, and virome immediately
- Maintain an anaerobic microenvironment
- Preserve molecular integrity for 3–5 days
- Support both human and animal research
This system enables multi-omics analysis at a level not achievable through fecal sampling alone.
The InOut Sampling Capsule
Our ingestible capsule is engineered to:
- Collect site-specific intestinal content
- Stabilize microbiota, metabolites, enzymes, and virome immediately
- Maintain an anaerobic microenvironment
- Preserve molecular integrity for 3–5 days
- Support both human and animal research
This system enables multi-omics analysis at a level not achievable through fecal sampling alone.
Connecting with the Scientific Community
We work with research groups exploring intestinal microbiology, metabolomics, digestive physiology, and cross-species comparisons.
Our focus is on enabling studies that require access to regional intestinal environments and the preservation of delicate molecular signatures.
Researchers interested in incorporating localized sampling into their work are welcome to reach out for more information.
